Wild Lettuce Tincture

Wild lettuce has a long history of use as a calming and comfort-supporting herb. Traditionally used in times of physical tension and restlessness, it has been appreciated for its ability to gently support the nervous system.

Its milky sap, known as lactucarium, contains naturally occurring compounds such as lactucin and lactucopicrin, which have been studied for their role in supporting relaxation and comfort.

Our wild lettuce is harvested from our own land in Sparta, Missouri, where it grows naturally and is never sprayed—offering a clean, truly wildcrafted botanical.

• Wild lettuce has been used historically since ancient times and into the 19th century.
• It was traditionally used for restlessness, cough, and physical discomfort.
• Its milky sap, called lactucarium, was once referred to as “lettuce opium” for its calming properties—though much milder.
• It grows abundantly in the wild, often overlooked despite its long history of use.

Traditionally used to support:

• Nervous system calm and relaxation
• Occasional muscle tension or physical discomfort
• Stress-related aches or tightness
• Restfulness and evening wind-down routines
• Overall comfort and ease

Take 1–2 dropperfuls, 1–2 times daily, or as needed.

May be taken directly under the tongue or added to a small amount of water or tea.

Often used in the evening or during periods of increased stress or physical tension.

Lactucin
Studied for its role in supporting relaxation and comfort.

Lactucopicrin
Associated with calming effects and support for the nervous system.

Sesquiterpene lactones
Contribute to the plant’s traditional use for easing tension and discomfort.

Bitter compounds
Support digestion and overall balance within the body.

This tincture may be especially supportive for:

• Those experiencing stress or restlessness
• Individuals with occasional muscle tension or discomfort
• Those seeking a gentle, plant-based way to unwind
• Individuals looking to support evening relaxation
• Anyone wanting to support calm and balance naturally

Wild lettuce (Lactuca spp.) has been studied for its potential calming and analgesic-supportive properties.

Research has explored compounds such as lactucin and lactucopicrin for their role in supporting relaxation and comfort, particularly in relation to the nervous system.

Much of the available research is preliminary, and as with many botanicals, its effects are often gentle and cumulative.

Featured Study: Analgesic and Sedative Activities of Lactucin and Lactucopicrin from Wild Lettuce

https://www.sciencedirect.com/science/article/abs/pii/S0378874106001280
Compounds naturally occurring in wild lettuce, including lactucin and lactucopicrin, have been studied for their analgesic and sedative activity in experimental models (animal), supporting the plant’s long history of traditional use for discomfort, restlessness, and nervous tension.

Traditionally, wild lettuce has been valued as a calming herb that supports the body’s natural ability to unwind and restore balance.

Wild Lettuce (Lactuca spp.)*, organic alcohol, distilled water, organic vegetable glycerin.

*Wildcrafted from our land in Sparta, Missouri.

Use caution when combining with other calming or sedative substances.

Not recommended during pregnancy.

Consult a healthcare provider if taking medications or managing a health condition.

Discontinue use if sensitivity occurs.